Azithromycin 250/500mg Tablets
Improves Clinical Outcome, Decreases Resistance
- Greater tissue penetration and an extended half-life of >60 hours
- Nonpolar and lipophilic molecule penetrate cell membranes
- within the cytosol, because of low pH, the drug is protonated and accumulates intracellularly
- ‘The Prolonged elimination half-life (6o hour s) allows once-daily dosing
- 20 times potent than erythromycin
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